Phenibut is a neuropsychotropic drug, derived from the neurotransmitter GABA that is capable of passing the blood-brain barrier. Phenibut is cited as a nootropic for its ability to improve neurological functions. It was discovered in Russia in the 1960's, and has since been used there to treat a wide range of ailments including anxiety and insomnia.
Who needs Phenibut?
All persons can benefit from phenibut supplementation due to its ability to induce relaxation and improve mental function. Phenibut supplementation may be especially efficacious for athletes and people living hectic, stress filled lifestyles.
What are Phenibuts Effects?
Nootropic effects: Although phenibut does not meet all the requirements of a nootropic, it does have many similarities to piracetam. In mice, phenibut causes significant improvement on the passive avoidance test . In this test of memory, animals are put in an undesirable area (such as a lighting situation or height from the floor that that species dislikes), and then given a negative stimulus (such as a shock) when they exit that area. Their ability to stay in the original area reflects how well they remember that if they exit it, they will receive the undesirable stimulus. Phenibut also improves performance on the swimming and rotarod tests and antagonizes the amnestic effect of chloramphenicol . It also has an antihypoxic effect, a trait commonly seen among nootropics . However, in one study, phenibut was ineffective in the water maze and shuttle box tests, while piracetam was . Other research supports the idea that phenibut has nootropic activity similar to that of piracetam, but not as strong . Nootropic activity has also been reported in humans , but it was not specified whether these were healthy adult humans, and they were probably elderly or psychiatric patients.
Another trait phenibut shares with nootropics is neuroprotection. Multiple animal studies have indicated that phenibut administration increases resistance to the detrimental effects of edema on mitochondria and energy production in the brain [20-22]. Phenibut also normalizes brain energy metabolism changes caused by chronic stress . It was found to prevent changes in plasma electrolytes caused by cerebral injury . Phenibut also protects dopaminergic neurons, and improved the condition of patients being treated with antiparkinsonic drugs .
Other effects: Phenibut has anticonvulsant activity against some drugs or conditions, but not others. It also potentiates the action of some other anticonvulsant drugs, and has been used to treat patients with epilepsy . Phenibut has been reported to reduce motion sickness, and used in the treatment of alcohol and morphine withdrawal [2, 26]. One study indicated that phenibut increased resistance to heat stress and improved working capacity in humans .
Why You Might Buy Phenibut?
To Relax Muscles
Increase Feeling of "Well Being"
If you need help sleeping
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