Differin Review - The "DL" on World's Most Popular Acne Medication

Easily the most popular prescription for acne is a Differin® (sometimes coupled with Benzaclin). Differin comes in three forms:

Differin Gel, 0.1%. This is the most common form of Differin. It is an acid that really digs deep into your pores. While it works, it can be quite painful and irritating to get there. The most common side effects are itchy, dry and cracked skin.

Differin Cream, 0.1%. Doctors will prescribe Differin Cream if you have a history of dry skin already, or if Differin gel is too painful.

Differin Gel, 0.3%. This is Differin's hardcore acne gel. Often, if Differin doesn't work, doctors will prescribe Accutane. Ask your doctor about Differin Gel, 0.3% before making that jump. It will be more severe than 0.1%, but not near as bad as Accutane.

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